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Local police officials said that the blast took place on Thursday in an area near Ghazni city, after a roadside bomb struck a car carrying civilians.
Reports say that the car was completely destroyed in the blast and another civilian was injured.
No group has claimed responsibility for the attacks. However, the Taliban has almost regularly been blamed for such instances of violence.
Earlier on Thursday, ten Afghan civilians were killed and eight others wounded in a bomb attack in the southern province of Uruzgan.
On Wednesday, a similar attack killed four Afghan civilians in Nozad district of the southern province of Helmand.
The militants use improvised explosive devices, including roadside bombs, against Afghan forces, foreign troops, and civilians.
In the first six months of 2012, over 1,140 Afghan civilians were killed and around 2,000 were wounded, mostly by roadside bombs, according to statistics released by the United Nations. Thirty percent of the casualties were women and children.
The United States and its allies invaded Afghanistan in 2001 as part of Washington’s so-called war on terror. The offensive removed the Taliban from power, but insecurity remains across the country.
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